You must read and accept the disclaimer to use this site. Updated when a question is received about this page.

Products relevant to nutrient signaling related to weight control

Weight loss index All indices Site Entry page

Disclaimer: I am not a physician, and by law, only physicians can give nutrition advice.  Therefore, this information is provided only for you to discuss with your physician.  The information is based on a weight loss clinical trial done in Spring, 2007.  For answers to questions, contact ordman@beloit.edu

HOW NUTRIENTS PROBABLY WORK

SUMMARY: Based on a double-blind placebo-controlled weight loss study of 67 people conducted in the spring of 2007, the following hypotheses were developed about how nutrient signaling might cause people to lose weight spontanenously. Three nutrients shown in Table 1 send signals to your body when taken in 5 gram doses zero to three hours before breakfast and again before your evening meal.

TABLE 1:HOW NUTRIENTS MAY WORK - Signals are explained in both technical and clear language (References are linked to the published articles)


Nutrient Signalling

Nutrient Class

Signal 1

Signal 2

Reference
J Nutrition

Leucine (BCAA)

Branched Chain Amino Acid (BCAA)

To the brain to decrease appetite; also to increase muscle mass

To the brain to increase metabolic rate

Sabatini et al. 1994

[signals your body to burn calories]

Oleic Acid
(Olive oil)

Polyunsaturated Fatty Acids

To adipose tissue to upregulate fat catabolism

To adipose tissue to downregulate lipid storage gene expression

Hsu and Huang 2006

[signals your fat cells to burn stored fat] [signals your fat cells to stop storing fat]

DHA

Omega-3 fatty acids

To adipocytes to inhibit differentiation

To pre-adipocytes to stimulate apoptosis

Kim et al. 2006

[signals your baby fat cells not to become fat  storage cells] [signals your potential fat cells to die before they become fat cells]

DOSAGE TO TRY: Below are suggestions to discuss with your health professional about how much to take and where to obtain these nutrients. Table 2 shows the various doses one can try. For instance, the lowest signal to lose weight is obtained by taking one-half capsule of branched chain amino acids (BCAA) and 1.25 tsp of olive oil before breakfast and again before dinner. It is suggested that young women and all men try this signal level first. If after two weeks, no weight has been loss, then progress to the medium signal level. Mature women should start at the medium level.

TABLE 2: WEIGHT LOSS SIGNAL LEVELS: try this much before breakfast and again before dinner, preferably 0 to 3 hours before eating.

Weight loss signal level

Leucine

(BCAA)

Olive

DHA

Young Male

Young

Female

Mature Male

Mature

Female

LOWEST

1/2 capsule (BCAA)

[2.5 g]

1.25 TSP

[2.5 g]

TRY THIS

TRY THIS

TRY THIS

MEDIUM

1capsule (BCAA)

[5 g]

2.5 TSP

[5 g]

 

 

TRY THIS

HIGHER

1capsule (BCAA

[5 g]

1.25 TSP

[2.5 g]

1 soft gel

[0.5g]

TRY THIS IF 1ST NOT SUFFICIENT

TRY THIS IF 1ST NOT SUFFICIENT

TRY THIS IF 1ST NOT SUFFICIENT

TRY THIS IF 1ST NOT SUFFICIENT

HIGHEST

1capsule (BCAA)

[5 g]

1.25 TSP

[2.5 g]

5 soft gels

[2.5g]

TRY THIS IF NEEDED

Please note that these products are expensive. ESTIMATED COST for materials per participant per day, besides purchase of extra virgin olive oil. are shown in Table 3.

TABLE 3: COST OF MATERIALS

Group

LOWEST

MEDIUM

HIGHER

HIGHEST

Cost/day

$0.15

$0.30

$2.30

$10.30

Cost/4 weeks

$4.50

$9.00

$70.00

$310.00

What to order initally

see 1-3 below for links to order

1 Bottle BCAA

1 Bottle BCAA

 

1 Bottle BCAA

1 BOTTLE DHA

1 Bottle BCAA

2 BOTTLES DHA

Expected Risks. There are no expected risks, except weight loss. It is acceptable for you to lose up to 2 pounds during any seven day period.  It might be useful to keep track of your waist-to-height ratio at http://home.fuse.net/clymer/bmi/. You should not go below a healthy waist-to-height ratio of  at least 43%. On days when you have lost more than that, do not take the regimen.  If there is any chance you may become pregnant, you should not do this.

WHERE TO ORDER NUTRIENTS [click on links to get to product web page- not affiliated with Nutrition Investigator]

1. Branched chain amino acid (BCAA) capsules - NSI BCAA's (Branched Chain Amino Acids) -- 2,400 mg - 300 Capsules, Our price: $19.99

2. Olive oil - Pick any brand of extra virgin olive oil.  Be sure to taste test it to make sure it is authentic, as nearly 50% of extra virgin olive oil may be phony.  Simply taste a small bit by putting a few drops on a spoon and swishing it around your mouth.  If the aftertaste is pleaseant, it is probably authentic.  If it has a bitter after taste, it is likely to be fake, probably hazelnut oil from Turkey.  Read the New Yorker article published in 2007 to learn  more.

3. DHA - called DHA Omega-3 Pharmaceutical Grade, 90 Softgels, 500mg, From Barlean, $1 per gel.  High dose DHA requires five in the morning and five before dinner, 10 per day. For low dose one can use one or more twice a day.

Disclaimer: I am not a physician, and by law, only physicians can give nutrition advice.  Therefore, this information is provided only for you to discuss with your physician.  The information is based on a weight loss clinical trial done in Spring, 2007.  For answers to questions, contact ordman@beloit.edu

You must read and accept the disclaimer to use this site.