You must read and accept the disclaimer to use this site. Updated for monthly, 2011

You must read and accept the disclaimer to use this site.

Vitamin B5, pantothenate

Vitamin: B5, pantothenic acid

Daily Value: 10 mg

Hazardous level: safe at more than 10xRDA

Average intake in US diet: 6 mg

Function: component of coenzyme A and acyl carrier protein, necessary for carrying two

carbon acyl groups in fat, protein, and carbohydrate metabolism

DOSAGE RATIONALE: Safe, so goal is at least 150% of RDA including dietary intake

KEY NOTES AND REFERENCES:

Alhadeff, L. et al, "Toxic effects of water-soluble vitamins", Nutr. Rev. 42: 33-40 (1984)

"it is now known that high doses of water-soluble vitamins may indeed have toxic effects"

Table II: vitamin disorder

nicotinic acid asthma, diabetes, liver, gout, cardiac, CNS

folate masks B12 deficiency, causes insomnia

pantothenate causes diarrhea

B1 causes irritability

B6 causes convulsions, antagonizes L-dopa in Parkinsons, neural troubles

- promotes diarrhea at 10g / day

WHITE PAPER REFERENCES FOR STAY WELL FORMULATIONS

no evidence of connection with colds, viruses, immune system

s...The circulating levels of biotin, pantothenate, riboflavin, vitamins A, B6,

B12, C, E, folate, Thiamine, nicotinate, and carotenes were determined in all groups."

"Thiamine, vitamin C and vitamin B12 levels were strikingly depressed in the non-institutional

elderly... Over 30% of the institutional elderly had vitamin B6 and nicotinate

hypovitaminemia...Both the institutional and the non-institutional elderly showed depressed

levels of folate and vitamin B12...Vitamin supplementation reduced the percentage of folate and

B12 deficits." - 29% of elderly were deficient

WHITE PAPER REFERENCES FOR STAY WELL FORMULATIONS

Chandra, R. K., "Effect of vitamin and trace-element supplementation on immune responses and

infection in elderly subjects", Lancet 340: 1124-27 (1992)

study of 96 people, had 23 vs. 48 days of illness, recipe 400 iu retinol, 16 mg beta-

carotene, 2.2 mg thiamin, 1.5 mg riboflavin, 16 mg niacin, 3 mg B6, 400 mcg folate, 4

mcg B12, 80 mg C, 4 mcg D, 44 mg E, 16 mg Iron, 200 mg Ca, 100 mg Mg

"thiamin, riboflavin, pyridoxine, ascorbic acid, retinol, alpha-tocopherol, folic acid,

cyanocobalanin, carotene and biotin status were assessed in a sample of 243 young

British adults... The status of ascorbic acid, cyanocobalamin, alpha-tocopherol, folic acid

and in males retinol, was adequate in the majority of cases. In the cases of riboflavin and

pyridoxine the status of a substantial minority was either borderline or deficient. The

thiamin and biotin status of a minority of both sexes, and retinol in the females, was

marginal" In riboflavin the status of a substantial minority of 243 British students was

either borderline or deficient.

WHITE PAPER REFERENCES FOR STAY WELL FORMULATIONS

Chandra, R. K., "Effect of vitamin and trace-element supplementation on immune responses and

infection in elderly subjects", Lancet 340: 1124-27 (1992)

study of 96 people, had 23 vs. 48 days of illness, recipe 400 iu retinol, 16 mg beta-

carotene, 2.2 mg thiamin, 1.5 mg riboflavin, 16 mg niacin, 3 mg B6, 400 mcg folate, 4

mcg B12, 80 mg C, 4 mcg D, 44 mg E, 16 mg Iron, 200 mg Ca, 100 mg Mg