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Irritable bowel

[inflammation and irritable bowels] Dirk Haller et al, Functional Diversity of Flavonoids in the Inhibition of the Proinflammatory NF-B, IRF, and Akt Signaling Pathways in Murine Intestinal Epithelial Cells

The molecular understanding of nutritional factors in the process of host factor–mediated activation of the intestinal epithelium may play an important role in the assessment of adjunct nutritional therapy for chronic intestinal inflammation. We characterized the molecular mechanisms of flavonoids ...In conclusion, we provide molecular evidence for the presence of characteristic inhibition patterns of these polyphenolic compounds to inhibit proinflammatory gene expression in [intestine cells] through the specific modulation of the NF-B, IRF and Akt signaling pathways... "Dietary flavonoids, which comprise the most comon group of plan polyphenols particularly abundant in fruits and vegetables, were shown to dmediate anti-inflammatory, anti-oxidative, antiproliferative, and proapoptotic effects in various cell types."

[inflammation and irritable bowels] Olga Martínez-Augustin et al, Goat Milk Oligosaccharides Are Anti-Inflammatory in Rats with Hapten-Induced Colitis

Oligosaccharides are included among the anti-inflammatory components of milk because of their prebiotic properties and their capacity to act as receptors of microorganisms. ..Thus, goat milk oligosaccharides have anti-inflammatory effects in rats with experimental colitis and may be useful in the management of inflammatory bowel disease.

[aged garlic extract provides benefits without odor component] Supplement: Significance of Garlic and Its Constituents in Cancer and Cardiovascular Disease